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Nephrology - Basic Science/Genetics News & Articles
MDLinx Nephrology is the one place you can find the most updated medical journal articles that focus on topics such as: kidney function, renal replacement therapy, immunosuppression management, clinical pharmacology, chronic kidney disease and much more. The articles found on MDLinx are thoroughly classified and expertly summarized by our team of medical editors, and then ranked to provide you optimal value for your time.
As a bonus you can check out our “must read” articles highlighted by our physician editor, D. Scott Cunningham, MD, PhD, along with clinical pearls from The Smartest Nephrologist daily quiz competition and review.
Become a member and get exclusive access to Nephrology career opportunities, e-newsletters that keep you updated with the latest medical literature, Category 1 & 2 CME credit opportunities as well as the ability to earn honoraria by participating in Market Research studies.
Your Unread Messages in Nephrology
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Articles
Latest (3) Full Text Articles (108) Focus on Cystic Kidney Disease361 Noninvasive Analyses of Kidney Injury Molecule-1 Messenger RNA in Kidney Transplant Recipients With Graft Dysfunction Transplantation Proceedings, October 11, 2012
362 p-Cresol sulfate and indoxyl sulfate induce similar cellular inflammatory gene expressions in cultured proximal renal tubular cells Nephrology Dialysis Transplantation, October 10, 2012
363 Polymorphism of the renalase gene in end-stage renal disease patients affected by hypertension Nephrology Dialysis Transplantation, October 9, 2012
364 Biphasic alveolosquamoid renal carcinoma: a histomorphological, immunohistochemical, molecular genetic, and ultrastructural study of a distinctive morphologic variant of renal cell carcinoma Annals of Diagnostic Pathology, October 4, 2012
365 In vitro reconstitution of human kidney structures for renal cell therapy Nephrology Dialysis Transplantation, October 3, 2012
366 In Vitro Microbiology Studies on a New Peritoneal Dialysis Connector Peritoneal Dialysis International, October 3, 2012
367 Regulatory T Cells Inhibit CD8+ T-Cell Tissue Invasion in Human Skin Graft-Versus-Host Reactions Transplantation, September 28, 2012
368 Renal involvement in a large cohort of Chinese patients with Castleman disease Nephrology Dialysis Transplantation, September 28, 2012
369 Evaluation of bioartificial renal tubule device prepared with lifespan-extended human renal proximal tubular epithelial cells Nephrology Dialysis Transplantation, September 27, 2012
370 P-cresol, but not p-cresylsulphate, disrupts endothelial progenitor cell function in vitro Nephrology Dialysis Transplantation, September 26, 2012
371 Decrease of Intracellular Chloride Concentration Promotes Endothelial Cell Inflammation by Activating Nuclear Factor-kB Pathway Hypertension, September 25, 2012
372 The renal (myo-)fibroblast: a heterogeneous group of cells Nephrology Dialysis Transplantation, September 24, 2012
373 Determination of the Nonlethal Margin Inside the Visible Ice-Ball During Percutaneous Cryoablation of Renal Tissue Cardiovascular and Interventional Radiology, September 19, 2012
374 Genetic variation in APOL1 and MYH9 genes is associated with chronic kidney disease among Nigerians International Urology and Nephrology, September 18, 2012
375 De Novo DQ Donor-Specific Antibodies Are Associated With a Significant Risk of Antibody-Mediated Rejection and Transplant Glomerulopathy Transplantation, September 18, 2012
376 The Role of Macrophage Lineage Cells in Kidney Graft Rejection and Survival Transplantation, September 14, 2012
377 Low Molecular Weight Heparin Decreases the Permeability of Glomerular Endothelial Cells when Exposed to Preeclampsia Serum in vitro Nephrology, September 11, 2012
378 Gene expression profiling of the synergy of 5-aza-2-deoxycytidine and paclitaxel against renal cell carcinoma World Journal of Surgical Oncology, September 7, 2012
379 The fate of bone marrow-derived cells carrying a polycystic kidney disease mutation in the genetically normal kidney BMC Nephrology, August 31, 2012
380 Orphan Kidney Diseases Nephron Clinical Practice, August 24, 2012
Clinical Pearls in Nephrology
- In patients with acute myocardial infarction, the hazard ratio (HR) for major adverse cardiac and cerebrovascular events (MACCE) was highest in patients with chronic kidney disease and anemia.
- Well-managed use of tobramycin long term is not associated with kidney failure. In a retrospective study among individuals with cystic fibrosis, the use of intravenous colistin, gentamicin, tobramycin or vancomycin did not correlate with increased BUN or creatinine after 8.5 years. Furthermore, only inhaled colistin correlated with kidney failure episodes
- Evidence by the Study of Heart and Renal Protection trial showed cardiovascular benefit and absence of special safety concerns for statin administration in chronic kidney disease; yet some experts call for additional data on renal outcomes.
Highlights in Nephrology
Risk factors for acute cardiac events in patients with community-acquired pneumonia
As published in the Journal of Infection, patients with community-acquired pneumonia (CAP) and acute cardiac events (ACEs) have a higher fatality rate (19.4%) than patients with CAP but without ACEs (6.4%). Of 3291 patients with CAP over a 15-year period, 315 had ACEs (8%; arrhythmias, n=199; congestive heart failure, n=118; myocardial infarction, n=30). Based on multivariate analysis, chronic heart disease, chronic kidney disease, tachycardia, septic shock, multilobar pneumonia, hypoalbuminemia, and pneumococcal pneumonia were associated with ACEs in patients with CAP.
Read the article summarySerum amyloid A is a sensitive biomarker for advanced renal cancer
Researchers from Martin Luther University Halle-Wittenberg (Germany) have reported that serum amyloid A (SAA) has greater sensitivity in detecting advanced renal tumors than CRP or IL-6 levels. Specifically, the sensitivities and specificities of SAA, CRP, and IL-6 for advanced renal tumors were 78%, 69%, and 44%, and 82%, 82%, and 94%, respectively. Furthermore, the SAA levels were higher in patients with advanced renal tumors than patients with localized renal tumors.
Read the article summaryNSAID-associated AKI more severe in young children
As published in the Journal of Pediatrics, NSAID-associated acute tubular necrosis and acute interstitial nephritis occurred in 21 and 6 of 1015 children with acute kidney injuries, respectively. Correct dosing of NSAIDs was confirmed in 75% of the children. Children < 5 years of age had more severe disease, more often requiring dialysis (100% vs. 0) and ICU admission (75% vs. 9%), and increased length of stay (10 d vs. 7 d).
Read the article summaryMost Popular Nephrology Articles
Last month's top read Top Articles of 2012Indexed Journals in Nephrology: Kidney International, Hemodialysis International, Nephrology Dialysis Transplantation more
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