Nephrology - Nephropathies News & Articles

MDLinx Nephrology is the one place you can find the most updated medical journal articles that focus on topics such as: kidney function, renal replacement therapy, immunosuppression management, clinical pharmacology, chronic kidney disease and much more. The articles found on MDLinx are thoroughly classified and expertly summarized by our team of medical editors, and then ranked to provide you optimal value for your time.

As a bonus you can check out our “must read” articles highlighted by our physician editor, D. Scott Cunningham, MD, PhD, along with clinical pearls from The Smartest Nephrologist daily quiz competition and review.

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Latest Full Text Articles (66) Focus on Cystic Kidney Disease

Ranked, sorted, and summarized by MDLinx editors from the latest literature

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1 Immunoglobulin M nephropathy in adults: a clinicopathological study Iranian Journal of Kidney Diseases, May 23, 2013 Clinical Article

2 Report on ISN Forefronts, Melbourne, Australia, 4-7 October 2012: tubulointerstitial disease in diabetic nephropathy Kidney International, May 23, 2013 Review Article

3 JC polyoma virus interacts with APOL1 in African Americans with nondiabetic nephropathy Kidney International, May 23, 2013 Review Article

4 Comparison of risk factors and outcomes in HIV immune complex kidney disease and HIV-associated nephropathy Clinical Journal of the American Society of Nephrology, May 22, 2013 Clinical Article

5 Border-crossers nephropathy: The risk of coming to America Renal Failure, May 22, 2013 Clinical Guideline Clinical Article

6 Renal lesions predict progression of diabetic nephropathy in type 1 diabetes Journal of the American Society of Nephrology, May 22, 2013 Clinical Article

7 Prognostic value of NGAL staining in patients with IgA nephropathy Renal Failure, May 22, 2013 Clinical Article

8 Pathology of recurrent diseases in kidney allografts: membranous nephropathy and focal segmental glomerulosclerosis Current Opinion in Organ Transplantation, May 21, 2013 Review Article

9 Acute Kidney Injury with Pigment Nephropathy Following Spider Bite: A Rarely Reported Entity in India Renal Failure, May 20, 2013

10 The Renal Endothelium in Diabetic Nephropathy Renal Failure, May 20, 2013 Review Article

11 Clinical Characteristics and Treatment of Patients with IgA Nephropathy and Hepatitis B Surface Antigen Renal Failure, May 20, 2013 Clinical Article

12 Trends in Incidence and Prevalence of Balkan Endemic Nephropathy in the Three Most Affected Villages in Serbia Over a 36-Year Period Renal Failure, May 20, 2013 Review Article

13 RAGE-mediated interstitial fibrosis in neonatal obstructive nephropathy is independent of NF-kB activation Kidney International, May 17, 2013 Review Article

14 The Safety and Short-Term Efficacy of Aliskiren in the Treatment of Immunoglobulin A Nephropathy - A Randomized Cross-Over Study PLOS ONE, May 15, 2013 Clinical Article

15 The long-term outcome of renal transplantation of IgA nephropathy and the impact of recurrence on graft survival Nephrology Dialysis Transplantation, May 15, 2013 Review Article

16 Fluctuation of serum C3 levels reflects disease activity and metabolic background in patients with IgA nephropathy Journal of Nephrology, May 14, 2013 Review Article

17 A novel TRPC6 mutation in a family with podocytopathy and clinical variability Full Text BMC Nephrology, May 13, 2013

18 Maintenance of Endothelial Guanosine Triphosphate Cyclohydrolase I Ameliorates Diabetic Nephropathy Journal of the American Society of Nephrology, May 9, 2013 Review Article

19 Reversibility of Structural and Functional Damage in a Model of Advanced Diabetic Nephropathy Journal of the American Society of Nephrology, May 9, 2013 Review Article

20 Immunosuppression for Membranous Nephropathy: A Systematic Review and Meta-Analysis of 36 Clinical Trials Clinical Journal of the American Society of Nephrology, May 8, 2013 Evidence Based Medicine Review Article Clinical Article

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Clinical Pearls in Nephrology

In patients with acute myocardial infarction, the hazard ratio (HR) for major adverse cardiac and cerebrovascular events (MACCE) was highest in patients with chronic kidney disease and anemia.
Well-managed use of tobramycin long term is not associated with kidney failure. In a retrospective study among individuals with cystic fibrosis, the use of intravenous colistin, gentamicin, tobramycin or vancomycin did not correlate with increased BUN or creatinine after 8.5 years. Furthermore, only inhaled colistin correlated with kidney failure episodes
Evidence by the Study of Heart and Renal Protection trial showed cardiovascular benefit and absence of special safety concerns for statin administration in chronic kidney disease; yet some experts call for additional data on renal outcomes.

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Highlights in Nephrology

Risk factors for acute cardiac events in patients with community-acquired pneumonia

As published in the Journal of Infection, patients with community-acquired pneumonia (CAP) and acute cardiac events (ACEs) have a higher fatality rate (19.4%) than patients with CAP but without ACEs (6.4%). Of 3291 patients with CAP over a 15-year period, 315 had ACEs (8%; arrhythmias, n=199; congestive heart failure, n=118; myocardial infarction, n=30). Based on multivariate analysis, chronic heart disease, chronic kidney disease, tachycardia, septic shock, multilobar pneumonia, hypoalbuminemia, and pneumococcal pneumonia were associated with ACEs in patients with CAP.

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Serum amyloid A is a sensitive biomarker for advanced renal cancer

Researchers from Martin Luther University Halle-Wittenberg (Germany) have reported that serum amyloid A (SAA) has greater sensitivity in detecting advanced renal tumors than CRP or IL-6 levels. Specifically, the sensitivities and specificities of SAA, CRP, and IL-6 for advanced renal tumors were 78%, 69%, and 44%, and 82%, 82%, and 94%, respectively. Furthermore, the SAA levels were higher in patients with advanced renal tumors than patients with localized renal tumors.

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NSAID-associated AKI more severe in young children

As published in the Journal of Pediatrics, NSAID-associated acute tubular necrosis and acute interstitial nephritis occurred in 21 and 6 of 1015 children with acute kidney injuries, respectively. Correct dosing of NSAIDs was confirmed in 75% of the children. Children < 5 years of age had more severe disease, more often requiring dialysis (100% vs. 0) and ICU admission (75% vs. 9%), and increased length of stay (10 d vs. 7 d).

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Most Popular Nephrology Articles

Last month's top read Top Articles of 2012

1 The preventive effect of pentoxifylline on contrast-induced nephropathy: a randomized clinical trial International Urology and Nephrology, April 12, 2013

2 Oxalate Nephropathy and Intravenous Vitamin C American Journal of Kidney Diseases, April 4, 2013

3 Angiotensin-converting enzyme (ACE) inhibitors for proteinuria and microalbuminuria in people with sickle cell disease Cochrane Reviews, April 1, 2013 Review Article

4 Combined Pancreas-Kidney Transplantation for Patients With End-Stage Nephropathy Caused by Type-2 Diabetes Mellitus Transplantation, April 22, 2013

5 Henoch-Schonlein purpura in a renal transplant recipient with prior IgA nephropathy following influenza vaccination Clinical Kidney Journal, April 15, 2013

6 NOD2 promotes renal injury by exacerbating inflammation and podocyte insulin resistance in diabetic nephropathy Kidney International, April 18, 2013 Review Article

7 Predictors of diabetic nephropathy Central European Journal of Medicine, April 23, 2013

8 The Treatment of Minimal Change Disease in Adults Journal of the American Society of Nephrology, March 6, 2013 Review Article

9 IgA nephropathy with severe chronic renal failure: a randomized controlled trial of corticosteroids and azathioprine Journal of Nephrology, February 12, 2013

10 Is a legacy effect possible in IgA nephropathy Nephrology Dialysis Transplantation, April 1, 2013 Review Article

11 Treatment of IgA nephropathy and Henoch–Schonlein nephritis Nature Reviews Nephrology, April 3, 2013

12 Immunosuppression for Membranous Nephropathy: A Systematic Review and Meta-Analysis of 36 Clinical Trials Clinical Journal of the American Society of Nephrology, March 1, 2013 Evidence Based Medicine

13 Pregnancy in Chronic Kidney Disease Advances In Chronic Kidney Disease , April 29, 2013 Review Article

14 BK polyoma virus nephropathy in the native kidney Nephrology Dialysis Transplantation, March 11, 2013 Review Article

15 The effects of diabetes mellitus and diabetic nephropathy on bone and mineral metabolism in T2DM patients Diabetes Research and Clinical Practice, April 5, 2013 Review Article

16 Intravenous Contrast Material–induced Nephropathy: Causal or Coincident Phenomenon Radiology, March 26, 2013

17 Detecting and controlling diabetic nephropathy: What do we know? Cleveland Clinic Journal of Medicine, April 3, 2013 Free full text

18 Treatment of idiopathic membranous nephropathy with combination of low-dose tacrolimus and corticosteroids Journal of Nephrology, February 27, 2013

19 Prevention of contrast-induced nephropathy with Na/K citrate European Heart Journal, January 28, 2013

20 Progression of diabetic nephropathy, risk of end-stage renal disease and mortality in patients with type-1 diabetes Saudi Journal of Kidney Diseases and Transplantation, March 27, 2013 Free full text

Indexed Journals in Nephrology: Kidney International, Hemodialysis International, Nephrology Dialysis Transplantation more

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Nephrology - Nephropathies News & Articles

Articles

Clinical Pearls in Nephrology

Highlights in Nephrology

Risk factors for acute cardiac events in patients with community-acquired pneumonia

Serum amyloid A is a sensitive biomarker for advanced renal cancer

NSAID-associated AKI more severe in young children

Most Popular Nephrology Articles

Other Topics in Nephrology