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Nephrology - Hematology/Oncology News & Articles
MDLinx Nephrology is the one place you can find the most updated medical journal articles that focus on topics such as: kidney function, renal replacement therapy, immunosuppression management, clinical pharmacology, chronic kidney disease and much more. The articles found on MDLinx are thoroughly classified and expertly summarized by our team of medical editors, and then ranked to provide you optimal value for your time.
As a bonus you can check out our “must read” articles highlighted by our physician editor, D. Scott Cunningham, MD, PhD, along with clinical pearls from The Smartest Nephrologist daily quiz competition and review.
Become a member and get exclusive access to Nephrology career opportunities, e-newsletters that keep you updated with the latest medical literature, Category 1 & 2 CME credit opportunities as well as the ability to earn honoraria by participating in Market Research studies.
Your Unread Messages in Nephrology
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Articles
Latest (3) Full Text Articles (117) Focus on Chronic Kidney Disease881 Phase 1 trial of everolimus plus sunitinib in patients with metastatic renal cell carcinoma Cancer, September 7, 2011 Clinical Article
882 Phase II trial of continuous once-daily dosing of sunitinib as first-line treatment in patients with metastatic renal cell carcinoma Cancer, September 7, 2011 Clinical Article
883 Atypical presentations and rare metastatic sites of renal cell carcinoma: a review of case reports Full Text Journal of Medical Case Reports, September 7, 2011
884 Long-term complete response to very-low-dose interleukin-2 therapy in patients with metastatic renal cell carcinoma: report of two cases Clinical and Experimental Nephrology, September 7, 2011 Clinical Article
885 Alcohol intake and risk of renal cell carcinoma: a meta-analysis of published case-control studies Archives of Medical Science, September 6, 2011 Evidence Based Medicine
886 A case of angiomyolipoma of the renal sinus Clinical and Experimental Nephrology, September 6, 2011
887 Molecular characterization of kidney cancer Cancer, September 2, 2011
888 Association of VEGF and VEGFR2 single nucleotide polymorphisms with hypertension and clinical outcome in metastatic clear cell renal cell carcinoma patients treated with sunitinib Cancer, September 2, 2011
889 Smoking negatively impacts renal cell carcinoma overall and cancer-specific survival Cancer, September 1, 2011
890 Epidermal growth factor receptor protein expression and genomic alterations in renal cell carcinoma Cancer, September 1, 2011
891 Urinary angiotensinogen levels in relation to renal involvement of Henoch-Schonlein purpura in children Nephrology, September 1, 2011
892 Incidence of Multiple Sporadic Renal Cell Carcinomas in Patients Referred for Renal Radiofrequency Ablation: Implications for Imaging Follow-Up American Journal of Roentgenology, September 1, 2011
893 5-Aza-2'-deoxycytidine enhances susceptibility of renal cell carcinoma to paclitaxel by decreasing LEF1/phospho-beta-catenin expression Cancer Letters, September 1, 2011
894 A case-control study of reproductive factors and renal cell carcinoma among black and white women in the United States Cancer Causes and Control, August 30, 2011
895 Characteristics of aggressive variants in T1a renal cell carcinoma Journal of Cancer Research & Clinical Oncology, August 30, 2011
896 Renal Cell Carcinoma with Unusual Metastasis to the Small Intestine Manifesting as Extensive Polyposis: Successful Management with Intraoperative Therapeutic Endoscopy Case Reports in Gastroenterology, August 30, 2011
897 Hypertension as a Predictive Factor for Survival Outcomes in Patients with Metastatic Renal Cell Carcinoma Treated with Sunitinib after Progression on Cytokines Kidney and Blood Pressure Research, August 29, 2011 Clinical Article
898 Sickle cell trait is not independently associated with susceptibility to end-stage renal disease in African Americans Kidney International, August 29, 2011
899 Inflammatory pseudotumor of the kidney: a case report Full Text Journal of Medical Case Reports, August 29, 2011
900 Elevated White Blood Cell Count Worsens Proteinuria but Not Estimated Glomerular Filtration Rate: The Kansai Healthcare Study American Journal of Nephrology, August 26, 2011
Clinical Pearls in Nephrology
- In patients with acute myocardial infarction, the hazard ratio (HR) for major adverse cardiac and cerebrovascular events (MACCE) was highest in patients with chronic kidney disease and anemia.
- Well-managed use of tobramycin long term is not associated with kidney failure. In a retrospective study among individuals with cystic fibrosis, the use of intravenous colistin, gentamicin, tobramycin or vancomycin did not correlate with increased BUN or creatinine after 8.5 years. Furthermore, only inhaled colistin correlated with kidney failure episodes
- Evidence by the Study of Heart and Renal Protection trial showed cardiovascular benefit and absence of special safety concerns for statin administration in chronic kidney disease; yet some experts call for additional data on renal outcomes.
Highlights in Nephrology
Risk factors for acute cardiac events in patients with community-acquired pneumonia
As published in the Journal of Infection, patients with community-acquired pneumonia (CAP) and acute cardiac events (ACEs) have a higher fatality rate (19.4%) than patients with CAP but without ACEs (6.4%). Of 3291 patients with CAP over a 15-year period, 315 had ACEs (8%; arrhythmias, n=199; congestive heart failure, n=118; myocardial infarction, n=30). Based on multivariate analysis, chronic heart disease, chronic kidney disease, tachycardia, septic shock, multilobar pneumonia, hypoalbuminemia, and pneumococcal pneumonia were associated with ACEs in patients with CAP.
Read the article summarySerum amyloid A is a sensitive biomarker for advanced renal cancer
Researchers from Martin Luther University Halle-Wittenberg (Germany) have reported that serum amyloid A (SAA) has greater sensitivity in detecting advanced renal tumors than CRP or IL-6 levels. Specifically, the sensitivities and specificities of SAA, CRP, and IL-6 for advanced renal tumors were 78%, 69%, and 44%, and 82%, 82%, and 94%, respectively. Furthermore, the SAA levels were higher in patients with advanced renal tumors than patients with localized renal tumors.
Read the article summaryNSAID-associated AKI more severe in young children
As published in the Journal of Pediatrics, NSAID-associated acute tubular necrosis and acute interstitial nephritis occurred in 21 and 6 of 1015 children with acute kidney injuries, respectively. Correct dosing of NSAIDs was confirmed in 75% of the children. Children < 5 years of age had more severe disease, more often requiring dialysis (100% vs. 0) and ICU admission (75% vs. 9%), and increased length of stay (10 d vs. 7 d).
Read the article summaryMost Popular Nephrology Articles
Last month's top read Top Articles of 20121 Uric Acid Levels Correlate with Baseline Renal Function and High Levels are a Potent Risk Factor for Postoperative Chronic Kidney Disease in Patients with Renal Cell Carcinoma The Journal of Urology, April 15, 2013
2 Is consumption of vegetables and fruit a protective factor against kidney cancer Central European Journal of Medicine, April 22, 2013
3 Angiotensin-converting enzyme (ACE) inhibitors for proteinuria and microalbuminuria in people with sickle cell disease Cochrane Reviews, April 1, 2013 Review Article
4 Bosniak IIF renal cysts: is there a malignancy potential Journal of Clinical Urology, April 1, 2013
5 Adverse Outcomes in Clear Cell Renal Cell Carcinoma with Mutations of 3p21 Epigenetic Regulators BAP1 and SETD2: a Report by MSKCC and the KIRC TCGA Research Network Clinical Cancer Research, April 26, 2013
6 The tumor suppressive function of UNC5D and its repressed expression in renal cell carcinoma Clinical Cancer Research, April 17, 2013 Review Article
7 Renal Medullary Carcinoma: Molecular, Immunohistochemistry, and Morphologic Correlation American Journal of Surgical Pathology , March 5, 2013
8 Prolonged exposure to tyrosine kinase inhibitors or early use of everolimus in metastatic renal cell carcinoma: are the two options alike Medical Oncology, April 29, 2013
9 Renal Cell Carcinoma: Role of MR Imaging in the Assessment of Muscular Venous Branch Invasion Radiology, April 23, 2013
10 Tetrandrine triggers apoptosis and cell cycle arrest in human renal cell carcinoma cells Journal of Natural Medicines, April 8, 2013
11 Patient-reported outcomes for axitinib vs sorafenib in metastatic renal cell carcinoma: phase III (AXIS) trial British Journal of Cancer, April 12, 2013
12 Clinical outcomes in patients receiving three lines of targeted therapy for metastatic renal cell carcinoma: Results from a large patient cohort European Journal of Cancer, April 25, 2013
13 Renal cell neoplasm of oncocytosis: a type of unclassified renal cell carcinoma Clinical and Experimental Nephrology Case Reports, April 24, 2013
14 Differential Diagnosis of Renal Tumors With Clear Cytoplasm: Clinical Relevance of Renal Tumor Subclassification in the Era of Targeted Therapies and Personalized Medicine Archives of Pathology & Laboratory Medicine, April 2, 2013 Free full text
15 Sequencing of Agents for Metastatic Renal Cell Carcinoma: Can We Customize Therapy European Urology, January 27, 2012 Free full text
16 Oral Adverse Events Associated with Tyrosine Kinase and Mammalian Target of Rapamycin Inhibitors in Renal Cell Carcinoma The Oncologist, January 30, 2012 Free full text
17 Indocyanine green (ICG)-based fluorescence navigation system for discrimination of kidney cancer from normal parenchyma: application during partial nephrectomy International Urology and Nephrology, January 13, 2012
18 Baseline quality of life as a prognostic survival tool in patients receiving sunitinib for metastatic renal cell carcinoma British Journal of Cancer, January 13, 2012
19 Efficacy and safety of vascular endothelial growth factor receptor tyrosine kinase inhibitors in patients with metastatic renal cell carcinoma and poor risk features Journal of Cancer Research & Clinical Oncology, January 19, 2012
20 T Lymphocyte Recruitment into Renal Cell Carcinoma Tissue: A Role for Chemokine Receptors CXCR3, CXCR6, CCR5, and CCR6 European Urology, January 30, 2012 Free full text
Indexed Journals in Nephrology: Kidney International, Hemodialysis International, Nephrology Dialysis Transplantation more
Other Topics in Nephrology
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