Nephrology - Hematology/Oncology News & Articles

MDLinx Nephrology is the one place you can find the most updated medical journal articles that focus on topics such as: kidney function, renal replacement therapy, immunosuppression management, clinical pharmacology, chronic kidney disease and much more. The articles found on MDLinx are thoroughly classified and expertly summarized by our team of medical editors, and then ranked to provide you optimal value for your time.

As a bonus you can check out our “must read” articles highlighted by our physician editor, D. Scott Cunningham, MD, PhD, along with clinical pearls from The Smartest Nephrologist daily quiz competition and review.

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Latest (1) Full Text Articles (117) Focus on Pediatric Nephrology

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41 Epithelioid angiomyolipoma of the kidney: pathological features and clinical outcome in a series of consecutively resected tumors Modern Pathology, April 22, 2013 Review Article

42 Colonic metastasis of a Renal Cell Carcinoma: Case report and brief review of the literature Central European Journal of Medicine, April 22, 2013 Review Article

43 A multi-peptide, dual-adjuvant telomerase vaccine (GX301) is highly immunogenic in patients with prostate and renal cancer Cancer Immunology, Immunotherapy, April 19, 2013 Clinical Article

44 A review of histopathological and immunohistochemical parameters in diagnosis of metastatic renal cell carcinoma with a case of gingival metastasis Journal of Cancer Research and Therapeutics, April 19, 2013 Review Article

45 Genistein downregulates onco-miR-1260b and inhibits Wnt-signalling in renal cancer cells British Journal of Cancer, April 18, 2013 Review Article

46 The tumor suppressive function of UNC5D and its repressed expression in renal cell carcinoma Clinical Cancer Research, April 17, 2013 Review Article

47 Renal cell carcinoma presenting with oral tongue metastasis: A rare case presentation Journal of Cancer Research and Therapeutics, April 17, 2013

48 Prognostic factors of metastatic renal cell carcinoma with extensive sarcomatoid component Journal of Cancer Research & Clinical Oncology, April 17, 2013 Clinical Article

49 Treatment of patients with metastatic renal cell carcinoma undergoing hemodialysis: case report of two patients and short literature review Full Text BMC Nephrology, April 17, 2013 Review Article

50 Sunitinib induces cellular senescence via p53/Dec1 activation in renal cell carcinoma cells Cancer Science, April 16, 2013 Clinical Article

51 Effect of different breathing patterns in the same patient on stereotactic ablative body radiotherapy dosimetry for primary renal cell carcinoma: A case study Medical Dosimetry, April 16, 2013

52 Uric Acid Levels Correlate with Baseline Renal Function and High Levels are a Potent Risk Factor for Postoperative Chronic Kidney Disease in Patients with Renal Cell Carcinoma The Journal of Urology, April 15, 2013 Clinical Article

53 Evolving therapeutic targets in renal cell carcinoma Current Opinion in Oncology, April 15, 2013 Clinical Article

54 Calcaneal acrometastasis from urothelial carcinoma of the ureter: a case report and literature review Full Text Clinical Interventions in Aging, April 15, 2013

55 Patient-reported outcomes for axitinib vs sorafenib in metastatic renal cell carcinoma: phase III (AXIS) trial British Journal of Cancer, April 12, 2013 Clinical Article

56 Health-related quality of life in Japanese patients with metastatic renal cell carcinoma treated with sunitinib International Journal of Clinical Oncology, April 12, 2013 Clinical Article

57 Toll-like receptor 9 agonist IMO cooperates with everolimus in renal cell carcinoma by interfering with tumour growth and angiogenesis British Journal of Cancer, April 12, 2013 Clinical Article

58 MicroRNA-141 is downregulated in human renal cell carcinoma and regulates cell survival by targeting CDC25B Full Text OncoTargets and Therapy, April 12, 2013

59 Laparoscopic partial nephrectomy of thyroid cancer metastasis: case report and review of the literature Full Text OncoTargets and Therapy, April 12, 2013 Clinical Article

60 Adenocarcinoma Ex Goblet Cell Carcinoid in a Renal Transplant Patient: A Case Report and Review of the Literature Anticancer Research, April 10, 2013

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Clinical Pearls in Nephrology

In patients with acute myocardial infarction, the hazard ratio (HR) for major adverse cardiac and cerebrovascular events (MACCE) was highest in patients with chronic kidney disease and anemia.
Well-managed use of tobramycin long term is not associated with kidney failure. In a retrospective study among individuals with cystic fibrosis, the use of intravenous colistin, gentamicin, tobramycin or vancomycin did not correlate with increased BUN or creatinine after 8.5 years. Furthermore, only inhaled colistin correlated with kidney failure episodes
Evidence by the Study of Heart and Renal Protection trial showed cardiovascular benefit and absence of special safety concerns for statin administration in chronic kidney disease; yet some experts call for additional data on renal outcomes.

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Highlights in Nephrology

Risk factors for acute cardiac events in patients with community-acquired pneumonia

As published in the Journal of Infection, patients with community-acquired pneumonia (CAP) and acute cardiac events (ACEs) have a higher fatality rate (19.4%) than patients with CAP but without ACEs (6.4%). Of 3291 patients with CAP over a 15-year period, 315 had ACEs (8%; arrhythmias, n=199; congestive heart failure, n=118; myocardial infarction, n=30). Based on multivariate analysis, chronic heart disease, chronic kidney disease, tachycardia, septic shock, multilobar pneumonia, hypoalbuminemia, and pneumococcal pneumonia were associated with ACEs in patients with CAP.

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Serum amyloid A is a sensitive biomarker for advanced renal cancer

Researchers from Martin Luther University Halle-Wittenberg (Germany) have reported that serum amyloid A (SAA) has greater sensitivity in detecting advanced renal tumors than CRP or IL-6 levels. Specifically, the sensitivities and specificities of SAA, CRP, and IL-6 for advanced renal tumors were 78%, 69%, and 44%, and 82%, 82%, and 94%, respectively. Furthermore, the SAA levels were higher in patients with advanced renal tumors than patients with localized renal tumors.

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NSAID-associated AKI more severe in young children

As published in the Journal of Pediatrics, NSAID-associated acute tubular necrosis and acute interstitial nephritis occurred in 21 and 6 of 1015 children with acute kidney injuries, respectively. Correct dosing of NSAIDs was confirmed in 75% of the children. Children < 5 years of age had more severe disease, more often requiring dialysis (100% vs. 0) and ICU admission (75% vs. 9%), and increased length of stay (10 d vs. 7 d).

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Most Popular Nephrology Articles

Last month's top read Top Articles of 2012

1 Uric Acid Levels Correlate with Baseline Renal Function and High Levels are a Potent Risk Factor for Postoperative Chronic Kidney Disease in Patients with Renal Cell Carcinoma The Journal of Urology, April 15, 2013

2 Is consumption of vegetables and fruit a protective factor against kidney cancer Central European Journal of Medicine, April 22, 2013

3 Angiotensin-converting enzyme (ACE) inhibitors for proteinuria and microalbuminuria in people with sickle cell disease Cochrane Reviews, April 1, 2013 Review Article

4 Bosniak IIF renal cysts: is there a malignancy potential Journal of Clinical Urology, April 1, 2013

5 Adverse Outcomes in Clear Cell Renal Cell Carcinoma with Mutations of 3p21 Epigenetic Regulators BAP1 and SETD2: a Report by MSKCC and the KIRC TCGA Research Network Clinical Cancer Research, April 26, 2013

6 The tumor suppressive function of UNC5D and its repressed expression in renal cell carcinoma Clinical Cancer Research, April 17, 2013 Review Article

7 Renal Medullary Carcinoma: Molecular, Immunohistochemistry, and Morphologic Correlation American Journal of Surgical Pathology , March 5, 2013

8 Prolonged exposure to tyrosine kinase inhibitors or early use of everolimus in metastatic renal cell carcinoma: are the two options alike Medical Oncology, April 29, 2013

9 Renal Cell Carcinoma: Role of MR Imaging in the Assessment of Muscular Venous Branch Invasion Radiology, April 23, 2013

10 Tetrandrine triggers apoptosis and cell cycle arrest in human renal cell carcinoma cells Journal of Natural Medicines, April 8, 2013

11 Patient-reported outcomes for axitinib vs sorafenib in metastatic renal cell carcinoma: phase III (AXIS) trial British Journal of Cancer, April 12, 2013

12 Clinical outcomes in patients receiving three lines of targeted therapy for metastatic renal cell carcinoma: Results from a large patient cohort European Journal of Cancer, April 25, 2013

13 Renal cell neoplasm of oncocytosis: a type of unclassified renal cell carcinoma Clinical and Experimental Nephrology Case Reports, April 24, 2013

14 Differential Diagnosis of Renal Tumors With Clear Cytoplasm: Clinical Relevance of Renal Tumor Subclassification in the Era of Targeted Therapies and Personalized Medicine Archives of Pathology & Laboratory Medicine, April 2, 2013 Free full text

15 Sequencing of Agents for Metastatic Renal Cell Carcinoma: Can We Customize Therapy European Urology, January 27, 2012 Free full text

16 Oral Adverse Events Associated with Tyrosine Kinase and Mammalian Target of Rapamycin Inhibitors in Renal Cell Carcinoma The Oncologist, January 30, 2012 Free full text

17 Indocyanine green (ICG)-based fluorescence navigation system for discrimination of kidney cancer from normal parenchyma: application during partial nephrectomy International Urology and Nephrology, January 13, 2012

18 Baseline quality of life as a prognostic survival tool in patients receiving sunitinib for metastatic renal cell carcinoma British Journal of Cancer, January 13, 2012

19 Efficacy and safety of vascular endothelial growth factor receptor tyrosine kinase inhibitors in patients with metastatic renal cell carcinoma and poor risk features Journal of Cancer Research & Clinical Oncology, January 19, 2012

20 T Lymphocyte Recruitment into Renal Cell Carcinoma Tissue: A Role for Chemokine Receptors CXCR3, CXCR6, CCR5, and CCR6 European Urology, January 30, 2012 Free full text

Indexed Journals in Nephrology: Kidney International, Hemodialysis International, Nephrology Dialysis Transplantation more

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Nephrology - Hematology/Oncology News & Articles

Articles

Clinical Pearls in Nephrology

Highlights in Nephrology

Risk factors for acute cardiac events in patients with community-acquired pneumonia

Serum amyloid A is a sensitive biomarker for advanced renal cancer

NSAID-associated AKI more severe in young children

Most Popular Nephrology Articles

Other Topics in Nephrology