Nephrology News & Articles

MDLinx Nephrology is the one place you can find the most updated medical journal articles that focus on topics such as: kidney function, renal replacement therapy, immunosuppression management, clinical pharmacology, chronic kidney disease and much more. The articles found on MDLinx are thoroughly classified and expertly summarized by our team of medical editors, and then ranked to provide you optimal value for your time.

As a bonus you can check out our “must read” articles highlighted by our physician editor, D. Scott Cunningham, MD, PhD, along with clinical pearls from The Smartest Nephrologist daily quiz competition and review.

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Articles

Latest (20) Full Text Articles (989) Focus on Nephrolithiasis

Ranked, sorted, and summarized by MDLinx editors from the latest literature

Topics:

941 Rho-kinase inhibition prevents the progression of diabetic nephropathy by downregulating hypoxia-inducible factor 1α Kidney International, May 3, 2013 Clinical Article

942 Indolic uremic solutes increase tissue factor production in endothelial cells by the aryl hydrocarbon receptor pathway Kidney International, May 3, 2013 Review Article

943 Effects of Targeted Interventions on Lifestyle Modifications of Chronic Kidney Disease Patients: Randomized Controlled Trial Western Journal of Nursing Research , May 2, 2013 Clinical Article

944 Raising awareness of acute kidney injury: a global perspective of a silent killer Kidney International, May 2, 2013 Clinical Article

945 Interventional Nephrology: Novel Devices that Will One Day Change Our Practice Clinical Journal of the American Society of Nephrology, May 2, 2013 Clinical Article

946 Incidence of Stroke Before and After Dialysis Initiation in Older Patients Journal of the American Society of Nephrology, May 2, 2013 Clinical Article

947 Serum n-3 and n-6 Polyunsaturated Fatty Acid Profile as an Independent Predictor of Cardiovascular Events in Hemodialysis Patients American Journal of Kidney Diseases, May 2, 2013 Clinical Article

948 Mineralocorticoid Receptor Blockade Reduced Oxidative Stress in Renal Transplant Recipients: A Double-Blind, Randomized Pilot Study American Journal of Nephrology, May 2, 2013 Clinical Article

949 Glomerular Filtration Rate Equations Overestimate Creatinine Clearance in Older Individuals Enrolled in the Baltimore Longitudinal Study on Aging: Impact on Renal Drug Dosing Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy, May 2, 2013 Clinical Article

950 A Novel Role for c-Myc in G Protein-Coupled Receptor Kinase 4 (GRK4) Transcriptional Regulation in Human Kidney Proximal Tubule Cells Hypertension, May 2, 2013 Review Article

951 Correlation between ICAM1 and VCAM1 gene polymorphisms and histopathological changes in kidney allograft biopsies Archives of Medical Science, May 2, 2013 Review Article

952 Regional variation in care at the end of life: discontinuation of dialysis Full Text BMC Geriatrics, May 2, 2013 Clinical Article

953 The Significance of Pretransplant Donor-Specific Antibodies Reactive with Intact or Denatured HLA in Kidney Transplantation Clinical and Experimental Immunology, May 2, 2013 Clinical Article

954 Rhabdomyolysis and Acute Renal Failure in a Sickle Cell Trait Athlete: A Case Study Clinical Journal of Sport Medicine, May 2, 2013

955 Factors potentially affecting the function of kidney grafts Full Text Chinese Medical Journal, May 2, 2013 Review Article

956 Long-term survivor of relapsed stage IV malignant rhabdoid tumor of the kidney Pediatrics International, May 2, 2013

957 Cinacalcet in Patients with Chronic Kidney Disease: A Cumulative Meta-Analysis of Randomized Controlled Trials Full Text PLoS Medicine, May 1, 2013 Evidence Based Medicine Clinical Article

958 Relation Between Circulating Levels of 25(OH) Vitamin D and Parathyroid Hormone in Chronic Kidney Disease: Quest for a Threshold Journal of Clinical Endocrinology and Metabolism, May 1, 2013 Clinical Article

959 Chronic kidney disease: Renal adenosine in hypertensive CKD Nature Reviews Nephrology, May 1, 2013 Clinical Article

960 Fibroblast Growth Factor 23, Klotho, and Disordered Mineral Metabolism in Chronic Kidney Disease: Unraveling the Intricate Tapestry of Events and Implications for Therapy Journal of Renal Nutrition, May 1, 2013 Clinical Article

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Clinical Pearls in Nephrology

In patients with acute myocardial infarction, the hazard ratio (HR) for major adverse cardiac and cerebrovascular events (MACCE) was highest in patients with chronic kidney disease and anemia.
Well-managed use of tobramycin long term is not associated with kidney failure. In a retrospective study among individuals with cystic fibrosis, the use of intravenous colistin, gentamicin, tobramycin or vancomycin did not correlate with increased BUN or creatinine after 8.5 years. Furthermore, only inhaled colistin correlated with kidney failure episodes
Evidence by the Study of Heart and Renal Protection trial showed cardiovascular benefit and absence of special safety concerns for statin administration in chronic kidney disease; yet some experts call for additional data on renal outcomes.

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Highlights in Nephrology

Risk factors for acute cardiac events in patients with community-acquired pneumonia

As published in the Journal of Infection, patients with community-acquired pneumonia (CAP) and acute cardiac events (ACEs) have a higher fatality rate (19.4%) than patients with CAP but without ACEs (6.4%). Of 3291 patients with CAP over a 15-year period, 315 had ACEs (8%; arrhythmias, n=199; congestive heart failure, n=118; myocardial infarction, n=30). Based on multivariate analysis, chronic heart disease, chronic kidney disease, tachycardia, septic shock, multilobar pneumonia, hypoalbuminemia, and pneumococcal pneumonia were associated with ACEs in patients with CAP.

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Serum amyloid A is a sensitive biomarker for advanced renal cancer

Researchers from Martin Luther University Halle-Wittenberg (Germany) have reported that serum amyloid A (SAA) has greater sensitivity in detecting advanced renal tumors than CRP or IL-6 levels. Specifically, the sensitivities and specificities of SAA, CRP, and IL-6 for advanced renal tumors were 78%, 69%, and 44%, and 82%, 82%, and 94%, respectively. Furthermore, the SAA levels were higher in patients with advanced renal tumors than patients with localized renal tumors.

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NSAID-associated AKI more severe in young children

As published in the Journal of Pediatrics, NSAID-associated acute tubular necrosis and acute interstitial nephritis occurred in 21 and 6 of 1015 children with acute kidney injuries, respectively. Correct dosing of NSAIDs was confirmed in 75% of the children. Children < 5 years of age had more severe disease, more often requiring dialysis (100% vs. 0) and ICU admission (75% vs. 9%), and increased length of stay (10 d vs. 7 d).

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Most Popular Nephrology Articles

Last month's top read Top Articles of 2012

1 Sevelamer Versus Calcium Carbonate in Incident Hemodialysis Patients: Results of an Open-Label 24-Month Randomized Clinical Trial American Journal of Kidney Diseases, May 21, 2013

2 Immunosuppression for Membranous Nephropathy: A Systematic Review and Meta-Analysis of 36 Clinical Trials Clinical Journal of the American Society of Nephrology, May 8, 2013 Evidence Based Medicine Review Article

3 Cinacalcet in Patients with Chronic Kidney Disease: A Cumulative Meta-Analysis of Randomized Controlled Trials PLoS Medicine, May 1, 2013 Free full text Evidence Based Medicine

4 Tripterygium Preparations for the Treatment of CKD: A Systematic Review and Meta-analysis American Journal of Kidney Diseases, May 14, 2013 Evidence Based Medicine Review Article

5 The absence of intrarenal ACE protects against hypertension The Journal of Clinical Investigation, May 7, 2013 Free full text

6 Integrins in Kidney Disease Journal of the American Society of Nephrology, May 6, 2013

7 Medical Management to Prevent Recurrent Nephrolithiasis in Adults: A Systematic Review for an American College of Physicians Clinical Guideline Annals of Internal Medicine, April 2, 2013 Evidence Based Medicine Review Article

8 Telenephrology: a novel approach to improve coordinated and collaborative care for chronic kidney disease Nephrology Dialysis Transplantation, April 1, 2013

9 NGAL and end stage renal disease: its not all about the kidneys! European Journal of Clinical Investigation, May 3, 2013

10 Cardiovascular toxicity of epoetin-alfa in patients with chronic kidney disease American Journal of Nephrology, May 30, 2013

11 Lifetime Incidence of CKD Stages 3-5 in the United States American Journal of Kidney Diseases, April 9, 2013

12 Effects of Oral Sodium Bicarbonate in Patients with CKD Clinical Journal of the American Society of Nephrology, May 8, 2013

13 Peritoneal dialysis-current status and future challenges Nature Reviews Nephrology, May 24, 2013 Review Article

14 Acute kidney injury: Perioperative sodium bicarbonate infusion for prevention of acute kidney injury-no benefit and possible harm Nature Reviews Nephrology, May 8, 2013

15 Association of Serum Bicarbonate With Risk of Renal and Cardiovascular Outcomes in CKD: A Report From the Chronic Renal Insufficiency Cohort (CRIC) Study American Journal of Kidney Diseases, March 14, 2013

16 Prevalence and Prognostic Role of Resistant Hypertension in Chronic Kidney Disease Patients JACC - Journal of the American College of Cardiology, May 10, 2013

17 Rasburicase in Tumor Lysis Syndrome of the Adult: A Systematic Review and Meta-analysis American Journal of Kidney Diseases, May 17, 2013 Evidence Based Medicine Review Article

18 Urinary Magnesium Excretion and Risk of Hypertension Hypertension, May 16, 2013

19 Cardiac Resynchronization Therapy in CKD: A Systematic Review Clinical Journal of the American Society of Nephrology, May 13, 2013 Evidence Based Medicine Review Article

20 Association between Dietary Sodium and Potassium Intake with Chronic Kidney Disease in US Adults: A Cross-Sectional Study American Journal of Nephrology, May 15, 2013

Indexed Journals in Nephrology: Kidney International, Hemodialysis International, Nephrology Dialysis Transplantation more

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Nephrology News & Articles

Articles

Clinical Pearls in Nephrology

Highlights in Nephrology

Risk factors for acute cardiac events in patients with community-acquired pneumonia

Serum amyloid A is a sensitive biomarker for advanced renal cancer

NSAID-associated AKI more severe in young children

Most Popular Nephrology Articles

Other Topics in Nephrology