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Unfavourable interaction of microalbuminuria and mildly reduced creatinine clearance on aortic stiffness in essential hypertension
International Journal of Cardiology, 12/14/2010
Mule G et al. – The aim of this study was to assess the independent relationships of urinary albumin excretion rate (AER), of creatinine clearance (CrCl) and of their interaction with aortic stiffness in hypertensive patients without overt renal insufficiency. In essential hypertensive patients microalbuminuria and mildly reduced CrCl are related independently of each other with increased carotid–femoral pulse wave velocity and exert a synergistic unfavourable effect on aortic stiffness.
