Acute kidney injury clinical trial design: old problems, new strategies
Pediatric Nephrology, 06/01/2012Endre ZH et al.
Apart from supportive dialysis there are no universally accepted interventions in acute kidney injury (AKI). The authors have summarized the outcomes of all published randomized, placebo–controlled studies of non–dialysis treatment of AKI. Forty–nine trials were identified, only one of which was in a paediatric population. Sixteen trials had positive outcomes; these trials are not comparable in terms of methodology used or outcomes assessed, and they share many of the problems of the negative trials.
MDLinx connects healthcare professionals and patients to tomorrow's important medical news, while providing the pharmaceutical and healthcare industries with highly targeted interactive marketing, education, content, and medical research solutions.