Electrocardiographic P-wave characteristics in patients with end-stage renal disease: P-index and interatrial block

International Urology and Nephrology, 05/16/2012

The present study demonstrated that interatrial block frequency and P index were increased in patients with end–stage renal disease.


  • Eighty-six HD, 47 CAPD, and 43 age- and gender-matched control subjects were enrolled in the study.
  • P-wave duration was measured in all 12-leads of the surface ECG.
  • The standard deviation of the P-wave duration across the 12 ECG leads was accepted as a Pi.
  • P-wave duration above and equal to 110 ms was defined as IAB.
  • All P-wave parameters were evaluated digitally by two observers.


  • Pi was found to be significantly different among the groups in ANOVA.
  • In post hoc analysis, P i was increased in HD group compared with the control group (p = 0.01).
  • Also, P i tended to increase in CAPD group compared with controls (p = 0.06).
  • The effect of ESRD on P i was independent of age, gender, and systolic blood pressure in univariate covariant analysis.
  • The prevalence of IAB was 61, 55, and 32 % in patients with HD, CAPD, and controls, respectively (p = 0.001).
  • P d was significantly higher in HD group compared with healthy controls.
  • However, Pd values of CAPD patients did not show significant difference compared with controls.

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