Hepatorenal Syndrome: A Severe, but Treatable, Cause of Kidney Failure in Cirrhosis

American Journal of Kidney Diseases, 04/10/2012

A liver transplant is the preferred treatment for Hepatorenal syndrome (HRS). Pharmacologic treatment with vasoconstrictors to reverse splanchnic vasodilation, together with albumin, is effective in 40%–50% of patients with type 1 HRS and improves survival. The drug of choice is the vasopressin analogue terlipressin. Renal replacement therapy should not be used as first–line therapy.

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