Vitamin D: The Iceberg Nutrient

Journal of Renal Nutrition, 03/25/2011

Armas LAG et al. - The article discusses vitamin D’s role in Cancer, cardiovascular disease and infections with a focus on the chronic kidney disease patient.

  • Patients with chronic kidney disease have a deficit in their kidney production of 1,25(OH)2D and have classically been treated with calcitriol or its active analogues.
  • Despite often having lower systemic levels of 1,25(OH)2D, patients with chronic kidney disease retain the capability of extra renal production of 1,25(OH)2D.
  • This has far reaching implications for their health.
  • This review examines clinical trials and observations in 3 areas that impact chronic kidney disease patients.
  • Cancer, cardiovascular disease and infections are responsible for much of the morbidity and mortality in this patient population.

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