Nephrology News & Articles

MDLinx Nephrology is the one place you can find the most updated medical journal articles that focus on topics such as: kidney function, renal replacement therapy, immunosuppression management, clinical pharmacology, chronic kidney disease and much more. The articles found on MDLinx are thoroughly classified and expertly summarized by our team of medical editors, and then ranked to provide you optimal value for your time.

As a bonus you can check out our “must read” articles highlighted by our physician editor, D. Scott Cunningham, MD, PhD, along with clinical pearls from The Smartest Nephrologist daily quiz competition and review.

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Articles

Latest (19) Full Text Articles (989) Focus on Pediatric Nephrology

Ranked, sorted, and summarized by MDLinx editors from the latest literature

Topics:

1 Rasburicase in Tumor Lysis Syndrome of the Adult: A Systematic Review and Meta-analysis American Journal of Kidney Diseases, May 17, 2013 Evidence Based Medicine Review Article Clinical Article

2 Soda and Other Beverages and the Risk of Kidney Stones Clinical Journal of the American Society of Nephrology, May 17, 2013 Clinical Article

3 Multipass haemodialysis: a novel dialysis modality Nephrology Dialysis Transplantation, May 17, 2013 Clinical Article

4 A new recombinant MnSOD prevents the Cyclosporine A-induced renal impairment Nephrology Dialysis Transplantation, May 17, 2013 Clinical Article

5 Sympathetic Nervous System Function and Dysfunction in Chronic Hemodialysis Patients Seminars in Dialysis, May 17, 2013 Review Article Clinical Article

6 Twenty-three-year review of disease patterns from renal biopsies: an experience from a pediatric renal center Journal of Nephrology, May 17, 2013 Clinical Article

7 Serum cystatin C as a marker of renal function in detection of early acute kidney injury Full Text Indian Journal of Nephrology, May 17, 2013 Clinical Article

8 Changing trends in the American diet over the past 38 years correlating to the increased prevalence of kidney stones Urology Times, May 17, 2013 Clinical Article

9 Direct Renin Inhibitor Induced Renal Failure American Journal of Therapeutics, May 17, 2013

10 Prevention of peritoneal dialysis catheter infections in Saudi peritoneal dialysis patients: the emergence of high-level mupirocin resistance The International Journal of Artificial Organs, May 17, 2013 Clinical Article

11 Dietary intake of fiber, vegetables, and fruit decrease the risk of incident kidney stones in women: a women's health initiative (WHI) report Urology Times, May 17, 2013 Clinical Article

12 Phase I study of highly selective inhibitor of VEGFR tyrosine kinase, tivozanib, in Japanese patients with solid tumors Cancer Science, May 17, 2013 Review Article

13 Increased incidence of herpes zoster in the setting of cytomegalovirus preemptive therapy after kidney transplantation Transplant Infectious Disease, May 17, 2013 Review Article

14 Impaired renal function is associated with mortality and morbidity after endovascular abdominal aortic aneurysm repair Journal of Vascular Surgery, May 17, 2013 Clinical Article

15 The effects of rhBMP-2 and Treg/Th17 functional disequilibrium in uremic patients with cardiovascular complication after maintenance hemodialysis The International Journal of Artificial Organs, May 17, 2013 Review Article

16 RAGE-mediated interstitial fibrosis in neonatal obstructive nephropathy is independent of NF-kB activation Kidney International, May 17, 2013 Review Article

17 Divergent functions of the Rho GTPases Rac1 and Cdc42 in podocyte injury Kidney International, May 17, 2013 Review Article

18 CD2AP is associated with end-stage renal disease in patients with type 1 diabetes Acta Diabetologia, May 17, 2013 Clinical Article

19 Impact of Hepatitis C Virus Infection on Bone Mineral Density in Renal Transplant Recipients PLOS ONE, May 17, 2013 Clinical Article

Prior Articles

20 Urinary Magnesium Excretion and Risk of Hypertension Hypertension, May 16, 2013 Clinical Article

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Clinical Pearls in Nephrology

In patients with acute myocardial infarction, the hazard ratio (HR) for major adverse cardiac and cerebrovascular events (MACCE) was highest in patients with chronic kidney disease and anemia.
Well-managed use of tobramycin long term is not associated with kidney failure. In a retrospective study among individuals with cystic fibrosis, the use of intravenous colistin, gentamicin, tobramycin or vancomycin did not correlate with increased BUN or creatinine after 8.5 years. Furthermore, only inhaled colistin correlated with kidney failure episodes
Evidence by the Study of Heart and Renal Protection trial showed cardiovascular benefit and absence of special safety concerns for statin administration in chronic kidney disease; yet some experts call for additional data on renal outcomes.

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Highlights in Nephrology

Risk factors for acute cardiac events in patients with community-acquired pneumonia

As published in the Journal of Infection, patients with community-acquired pneumonia (CAP) and acute cardiac events (ACEs) have a higher fatality rate (19.4%) than patients with CAP but without ACEs (6.4%). Of 3291 patients with CAP over a 15-year period, 315 had ACEs (8%; arrhythmias, n=199; congestive heart failure, n=118; myocardial infarction, n=30). Based on multivariate analysis, chronic heart disease, chronic kidney disease, tachycardia, septic shock, multilobar pneumonia, hypoalbuminemia, and pneumococcal pneumonia were associated with ACEs in patients with CAP.

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Serum amyloid A is a sensitive biomarker for advanced renal cancer

Researchers from Martin Luther University Halle-Wittenberg (Germany) have reported that serum amyloid A (SAA) has greater sensitivity in detecting advanced renal tumors than CRP or IL-6 levels. Specifically, the sensitivities and specificities of SAA, CRP, and IL-6 for advanced renal tumors were 78%, 69%, and 44%, and 82%, 82%, and 94%, respectively. Furthermore, the SAA levels were higher in patients with advanced renal tumors than patients with localized renal tumors.

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NSAID-associated AKI more severe in young children

As published in the Journal of Pediatrics, NSAID-associated acute tubular necrosis and acute interstitial nephritis occurred in 21 and 6 of 1015 children with acute kidney injuries, respectively. Correct dosing of NSAIDs was confirmed in 75% of the children. Children < 5 years of age had more severe disease, more often requiring dialysis (100% vs. 0) and ICU admission (75% vs. 9%), and increased length of stay (10 d vs. 7 d).

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Most Popular Nephrology Articles

Last month's top read Top Articles of 2012

1 Telenephrology: a novel approach to improve coordinated and collaborative care for chronic kidney disease Nephrology Dialysis Transplantation, April 1, 2013

2 Lifetime Incidence of CKD Stages 3-5 in the United States American Journal of Kidney Diseases, April 9, 2013

3 Medical Management to Prevent Recurrent Nephrolithiasis in Adults: A Systematic Review for an American College of Physicians Clinical Guideline Annals of Internal Medicine, April 2, 2013 Evidence Based Medicine Review Article

4 Computed Tomography Angiography in the Diagnosis of ANCA-Associated Small- and Medium-Vessel Vasculitis American Journal of Kidney Diseases, April 15, 2013

5 Association of Serum Bicarbonate With Risk of Renal and Cardiovascular Outcomes in CKD: A Report From the Chronic Renal Insufficiency Cohort (CRIC) Study American Journal of Kidney Diseases, March 14, 2013

6 The preventive effect of pentoxifylline on contrast-induced nephropathy: a randomized clinical trial International Urology and Nephrology, April 12, 2013

7 Effects of Oral Sodium Bicarbonate in Patients with CKD Clinical Journal of the American Society of Nephrology, February 13, 2013

8 Oxalate Nephropathy and Intravenous Vitamin C American Journal of Kidney Diseases, April 4, 2013

9 The GFR and GFR decline cannot be accurately estimated in type 2 diabetics Kidney International, March 7, 2013 Review Article

10 Antiplatelet Therapy in the Management of Cardiovascular Disease in Patients with CKD: What Is the Evidence Clinical Journal of the American Society of Nephrology, April 8, 2013 Evidence Based Medicine Review Article

11 Hematuria and risk for end-stage kidney disease Current Opinion in Nephrology and Hypertension, April 24, 2013

12 The Complement Cascade in Kidney Disease: From Sideline to Center Stage American Journal of Kidney Diseases, March 28, 2013 Review Article

13 Hyponatremia: an update on current pharmacotherapy Expert Opinion on Pharmacotherapy, April 15, 2013

14 Dietary Sugar and Artificial Sweetener Intake and Chronic Kidney Disease: A Review Advances In Chronic Kidney Disease , March 1, 2013 Review Article Clinical Guideline

15 New treatments for autosomal dominant polycystic kidney disease British Journal of Clinical Pharmacology, April 19, 2013 Review Article

16 Clinical and experimental use of probiotic formulations for management of end-stage renal disease: an update International Urology and Nephrology, April 17, 2013

17 Bone Alkaline Phosphatase in CKD-Mineral Bone Disorder American Journal of Kidney Diseases, April 26, 2013

18 Dialysate Calcium Concentration and Mineral Metabolism in Long and Long-Frequent Hemodialysis: A Systematic Review and Meta-analysis for a Canadian Society of Nephrology Clinical Practice Guideline American Journal of Kidney Diseases, April 16, 2013 Evidence Based Medicine

19 Statins decrease all-cause mortality only in CKD patients not requiring dialysis therapy - a meta-analysis of 11 randomized controlled trials involving 21,295 participants Pharmacological Research , April 3, 2013 Evidence Based Medicine

20 Dietary Sodium: A Therapeutic Target in the Treatment of Hypertension and CKD Journal of Renal Nutrition, April 23, 2013

Indexed Journals in Nephrology: Kidney International, Hemodialysis International, Nephrology Dialysis Transplantation more

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Nephrology News & Articles

Articles

Prior Articles

Clinical Pearls in Nephrology

Highlights in Nephrology

Risk factors for acute cardiac events in patients with community-acquired pneumonia

Serum amyloid A is a sensitive biomarker for advanced renal cancer

NSAID-associated AKI more severe in young children

Most Popular Nephrology Articles

Other Topics in Nephrology