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Pdx-1 Regulation of the INGAP Promoter Involves Sequestration of NeuroD Into a Non-DNA-Binding Complex
Pancreas, 12/18/09
Taylor–Fishwick DA et al. – The data reveal a dynamic interaction between Pdx–1, NeuroD, and Pan–1 for the regulation of INGAP promoter activity. Modulating molecular regulators of DNA expression may be a consideration in diabetic therapies that translate exogenous stimuli into new endogenous beta–cell mass.
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