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Management of Hypercholesterolemia
Geriatrics & Aging, 11/10/09

Aronow WS – The updated National Cholesterol Education Program (NCEP) III guidelines state that in very–high–risk patients, a serum low–density lipoprotein (LDL) cholesterol level of <1.81 mmol/L (<70 mg/dL) correct is a reasonable clinical strategy, regardless of age. When a high–risk person has hypertriglyceridemia or low serum high–density lipoprotein cholesterol, consideration can be given to combining a fibrate or nicotinic acid with an LDL cholesterol–lowering drug. For moderately high–risk persons, the serum LDL cholesterol should be reduced to <2.59 mmol/L 2.59 (<100 mg/dL). When LDL cholesterol–lowering drug therapy is used to treat high–risk persons or moderately high–risk persons, the serum LDL cholesterol should be reduced by at least 30–40%. High–risk older persons should be treated with lipid–lowering drug therapy according to NCEP III updated guidelines to reduce cardiovascular morbidity and mortality. The LDL cholesterol should be reduced to <4.14 mmol/L (<160 mg/dL)correct in persons at low risk for cardiovascular disease.

Self-Reported Adherence to Nonpharmacological Treatment and Association with Mortality over 6 Years: Population-Based Study in Older Persons with Hypercholesterolemia
Journal of the American Geriatrics Society, 10/28/09 Relevance Score: 88%

U.S. Food and Drug Administration approves CRESTOR for use in pediatric patients with heterozygous familial hypercholesterolemia
AstraZeneca, 10/19/09 Relevance Score: 84%

Suppressive effect of EPA on the incidence of coronary events in hypercholesterolemia with impaired glucose metabolism: Sub-analysis of the Japan EPA Lipid Intervention Study (JELIS)
Atherosclerosis, 10/14/09 Relevance Score: 84%

Increased oxidative stress levels and normal antioxidant enzyme activity in circulating mononuclear cells from patients of familial hypercholesterolemia
Metabolism-Clinical and Experimental, 10/13/09 Relevance Score: 84%

The Effect of Hypercholesterolemia on Rotator Cuff Disease
Clinical Orthopedics and Related Research, 11/13/09 Relevance Score: 83%

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Today in Endocrinology...keeping you current

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Today in Family Medicine...keeping you current

Clinic Systems and the Quality of Care for Older Adults in Residency Clinics and in Physician Practices
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Best Practice & Research Clinical Endocrinology & Metabolism, 12/04/09

Narcolepsy: Clinical Decision Making for the Primary Care Physician
Southern Medical Journal, 12/04/09

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Today in Internal Medicine...keeping you current

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