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Successful treatment of immune reconstitution inflammatory syndrome in Whipples disease using thalidomide
Journal of Infection, 11/10/09
Lagier JC et al. – A patient with classic Whipple's disease developed erythema nodosum leprosum–like lesions and fever one month after the beginning of an accurate therapy with trimethoprim–sulfamethoxazole. Immune reconstitution inflammatory syndrome was suspected, but corticosteroid therapy failed to improve the patient. Finally, thalidomide was used and successfully induced rapid improvement.
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