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Acid and Weakly Acidic Solutions Impair Mucosal Integrity of Distal Exposed and Proximal non-Exposed Human Oesophagus
Gut, 11/09/09
Sifrim D et al. – Human oesophageal mucosa is very sensitive to continuous exposure with acidic and weakly acidic solutions. In spite of the presence of intraluminal acid and DIS, healthy subjects did not experience heartburn, suggesting that NERD patients should have other critical factors underlying their symptoms.
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