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See Latest ArticlesMechanisms of human insulin resistance and thiazolidinedione-mediated insulin sensitization
Proceedings of the National Academy of Sciences of the United States of America, 11/04/09
Sears DD et al. – Pre–TZD treatment expression of MLXIP in muscle and HLA–DRB1 in adipose tissue from insulin resistant subjects was linearly predictive of post–TZD insulin sensitization. We have uniquely characterized coordinated cellular and tissue functional pathways that are characteristic of insulin resistance, TZD–induced insulin sensitization, and potential TZD responsiveness.
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