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Osteonecrosis of the jaw correlated to bisphosphonate therapy in non-oncologic patients: Clinicopathological features of 24 patients
Journal of Rheumatology, 11/09/09
Favia G et al. – ONJ is a harmful side effect of bisphosphonate therapies. Clinicians must be aware of this entity, inform patients of the risks related to dental surgery, and possibly undertake adequate preventive measures.
Methods- Over 4 year period, total of 102 bisphosphonate-treated patients affected by ONJ identified
- 24 patients underwent bisphosphonate therapy for non-neoplastic disease and profile analyzed
- In study cohort, bisphosphonates administered mainly for postmenopausal osteoporosis (20/24 patients, 83.3%)
- Duration of therapy until presentation of ONJ ranging from 11 to 40 months
- Most common triggering event dentoalveolar surgery
- All patients nonsmokers
- 6 manifested multiple ONJ lesions
- 3 had possible comorbidities
- Surgical debridement performed in 19 patients for total of 22 lesions, which were individually considered in followup
- Latter showed complete remission of ONJ in 21/22 lesions
Today in Bone Metabolism...keeping you current
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Overexpression of heme oxygenase-1 increases human osteoblast stem cell differentiation
Journal of Bone and Mineral Metabolism, 11/23/09
High pressure may inhibit periprosthetic osteogenesis
Journal of Bone and Mineral Metabolism, 11/23/09
Today in Clinical Pharmacology...keeping you current
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Serum Thyroid-Stimulating Hormone Concentration and Morbidity from Cardiovascular Disease and Fractures in Patients on Long-Term Thyroxine Therapy
Journal of Clinical Endocrinology and Metabolism, 11/24/09
Adult Cyclic Vomiting Syndrome Successfully Treated with Intranasal Sumatriptan
Journal of General Internal Medicine, 11/24/09
Aminoglycoside therapy against Pseudomonas aeruginosa in cystic fibrosis: A review
Journal of Cystic Fibrosis , 11/24/09
Today in Orthopedic/Physical Med...keeping you current
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Acupuncture Treatment for Plantar Fasciitis: A Randomized Controlled Trial with Six Months Follow-up
Evidence-based Complementary and Alternative Medicine , 11/24/09
An epidemiological survey of low back pain and axial spondyloarthritis in a Chinese Han population
Scandinavian Journal of Rheumatology , 11/24/09
Small bone lesions resembling erosions can frequently be found in bilateral wrist MRI of healthy individuals
Scandinavian Journal of Rheumatology , 11/24/09
Today in Clinical Pharmacology...keeping you current
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Serum Thyroid-Stimulating Hormone Concentration and Morbidity from Cardiovascular Disease and Fractures in Patients on Long-Term Thyroxine Therapy
Journal of Clinical Endocrinology and Metabolism, 11/24/09
Adult Cyclic Vomiting Syndrome Successfully Treated with Intranasal Sumatriptan
Journal of General Internal Medicine, 11/24/09
A network meta-analysis of randomized controlled trials of biologics for rheumatoid arthritis: a Cochrane overview
Canadian Medical Association Journal, 11/24/09
Today in Rheumatology...keeping you current
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A network meta-analysis of randomized controlled trials of biologics for rheumatoid arthritis: a Cochrane overview
Canadian Medical Association Journal, 11/24/09
Is osteoarthritis a heterogeneous disease that can be stratified into subsets?
Clinical Rheumatology, 11/24/09
Low plasma levels of monocyte chemoattractant protein-1 (MCP-1), tumor necrosis factor-alpha (TNF &alpha), and vascular endothelial growth factor (VEGF) in patients with alpha1-antitrypsin deficiency-related fibromyalgia
Clinical Rheumatology, 11/24/09
Today in Bone Metabolism...keeping you current
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Evaluation and management of osteoporosis and fragility fractures in the elderly
Aging Health, 11/23/09
Increased Dickkopf-1 expression accelerates bone cell apoptosis in femoral head osteonecrosis
Bone , 11/23/09
Serum TSH values and risk of vertebral fractures in euthyroid post-menopausal women with low bone mineral density
Bone , 11/20/09
Today in Bone Metabolism...keeping you current
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Evaluation and management of osteoporosis and fragility fractures in the elderly
Aging Health, 11/23/09
Serum TSH values and risk of vertebral fractures in euthyroid post-menopausal women with low bone mineral density
Bone , 11/20/09
Today in Clinical Pharmacology...keeping you current
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A network meta-analysis of randomized controlled trials of biologics for rheumatoid arthritis: a Cochrane overview
Canadian Medical Association Journal, 11/24/09
The beneficial effects of a 3 week course of intramuscular glucocorticoid injections in patients with very early inflammatory polyarthritis: Results of the STIVEA trial
Annals of Rheumatic Diseases, 11/24/09
Effect of Sildenafil on digital ulcers in systemic sclerosis - analysis from a single centre pilot study
Annals of Rheumatic Diseases, 11/23/09
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