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Pythium insidiosum keratitis in an Australian child
Clinical and Experimental Ophthalmology, 11/03/09

Badenoch PR et al. – The identification of the organism was confirmed by rRNA gene sequencing. P. insidiosum is an oomycete, an organism more closely related to kelp than to fungi. Masses of hyphae were seen in sections and, for the first time, the ultrastructure of P. insidiosum in human tissue is described. The staining characteristics of cultured hyphae were assessed; lactofuchsin and acridine orange were found to be the most useful methods. Although the diagnosis of P. insidiosum keratitis is not difficult, and the organism is susceptible in vitro to a number of antimicrobial agents, early corneal transplantation remains the treatment of choice.

Successful Use of Topical Voriconazole 1% Alone as First-Line Antifungal Therapy Against Candida albicans Keratitis
Annals of Pharmacotherapy, 10/28/09 Relevance Score: 89%

Rapid detection of fungal keratitis using DNA-stabilizing FTA filter paper
Investigative Ophthalmology and Visual Science, 11/04/09 Relevance Score: 87%

Fungal Keratitis With Intracameral Extension Following Penetrating Keratoplasty
Cornea, 10/14/09 Relevance Score: 87%

Corneal neovascularization during experimental fungal keratitis
Molecular Vision, 10/01/09 Relevance Score: 87%

Burkholderia cepacia keratitis with endophthalmitis
Journal of Medical Microbiology, 10/21/09 Relevance Score: 85%