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IL-18 Downregulates Collagen Production in Human Dermal Fibroblasts via the ERK Pathway
Journal of Investigative Dermatology, 11/03/09
Park HP et al. – The authors data indicate that IL–18 downregulates collagen production in HDF directly via Ets–1 and the ERK pathway, suggesting that IL–18 may exert antifibrotic activities in dermal fibroblasts.
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