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Magkos F et al. – The effect of exercise on the plasma concentration of high–molecular weight (HMW) adiponectin (i.e., the biologically active form of circulating adiponectin) and the possible role of HMW adiponectin in mediating the exercise–induced enhancement of insulin action are not known. The aim of this study was to evaluate the relationship between the post–exercise increase in insulin sensitivity and plasma HMW adiponectin concentration. Changes in HMW adiponectin concentration are not involved in the acute exercise–induced enhancement of insulin action.

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