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Why does diabetes offer protective effects against prostate cancer? The possible role of its microvascular complications
Medical Hypotheses, 11/04/09

Weiwei Z et al. – The typical histological changes of microvascular lesions are capillary basement membrane thickening, capillary occlusion and degeneration, eventually capillary dysfunction and organ ischemia. Therefore, the authors hypothesize that DM might induce local microvascular dysfunction and prostate ischemia, which prevent initiation and development of CaP. Currently, numerous studies showing effect of anti–angiogenesis therapy on CaP strongly support the hypothesis.

Prevention of Type 2 Diabetes: Risk Status, Clinic, and Community
Journal of General Internal Medicine, 11/09/09 Relevance Score: 96%

Differential association of HLA with three subtypes of type 1 diabetes: fulminant, slowly progressive and acute-onset
Diabetologia - Clinical and Experimental Diabetes and Metabolism, 10/19/09 Relevance Score: 95%

Cigarette smoking is an independent risk factor for type 2 diabetes: a four-year community-based prospective study
Clinical Endocrinology, 10/16/09 Relevance Score: 94%

Periodontal Disease – The Overlooked Diabetes Complication
Nephrology Nursing Journal, 10/07/09 Relevance Score: 94%

Testing for monogenic diabetes among children and adolescents with antibody-negative clinically defined Type 1 diabetes
Diabetic Medicine, 10/05/09 Relevance Score: 94%