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See Latest ArticlesSKP2 and CKS1 Promote Degradation of Cell Cycle Regulators and Are Associated With Hepatocellular Carcinoma Prognosis
Gastroenterology, 10/29/09
Calvisi DF et al. – Ubiquitination and proteasome degradation of P21WAF1, P27KIP1, P57KIP2, P130, RASSF1A, and FOXO1 and mechanisms that prevent degradation of SKP2 by APC/C–CDH1 contribute to HCC progression. CKS1–SKP2 ligase might be developed as a therapeutic target or diagnostic marker.
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The 5-HT4 receptor agonist mosapride attenuates NSAID-induced gastric mucosal damage
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