Med Student Medical News about Gastrointestinal Tract Hemorrhage Platelet Aggregation Inhibitors

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A comparison of aspirin and clopidogrel with or without proton pump inhibitors for the secondary prevention of cardiovascular events in patients at high risk for gastrointestinal bleeding
Clinical Therapeutics, 10/28/09

Hsiao F–Y et al. – In this analysis in patients at high GI risk who were receiving antiplatelet therapy for the secondary prevention of cardiovascular events, aspirin plus a PPI was associated with a reduced risk of recurrent hospitalization for major GI complications. This was not the case for clopidogrel plus a PPI.