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Down-regulation of intrahepatic CD16+ and CD56+ immune cells in chronic Hepatitis C virus infection and HCV-related hepatocellular carcinoma
Archives of Medical Science, 11/02/09
Bassiouny AE et al. – The data show that CHC is associated with defects in NK cells and CD56+ lymphocytes that correlate with the degree of inflammatory activity and stage of hepatic fibrosis. The reduced CD16+ Kupffer cells in chronic HCV infection and HCC stress the important role of these cells in antiviral and antitumor immunity.
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