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Comparison of Interferon-gamma release assays and Tuberculin Skin Test in predicting active tuberculosis in children in the UK
BMJ - Archives of Diseases in Childhood, 10/30/09

Bamford ARJ et al. – Neither IGRA performed significantly better than a TST with a cut–off of 15 mm. Combining results of TST and IGRA increased the sensitivity to 96% for TST plus T–Spot.TB and 91% for TST plus QFG–IT in the definite TB cohort. A negative IGRA does not exclude active TB disease, but a combination of TST and IGRA increases the sensitivity for identifying children with active TB.