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Reduced gamma-Catenin Expression and Poor Survival in Oral Squamous Cell Carcinoma
Archives of Otolaryngology, 10/26/09
Narkio–Makela M et al. – Reduced expression of gamma–catenin was associated with poor differentiation of OSCC, with neck lymph node metastases, and, more importantly, with poor disease–specific survival. Loss of gamma–catenin expression seems to contribute to metastatic properties of OSCC. Evaluation of the expression pattern of gamma–catenin may be useful for predicting outcome in patients with OSCC.
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