Med Student Medical News about Keratoderma, Palmoplantar

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Extra-palmoplantar lesions associated with palmoplantar pustulosis
Journal of the European Academy of Dermatology and Venereology, 10/26/09

Yamamoto T – The findings suggest a close relationship between PPP and psoriasis; however, different genetic, environmental, and immunological factors are likely to be involved. Recently, understanding of psoriasis pathophysiology has greatly progressed, and the concept of psoriasis pathogenesis is currently viewed as complicated responses between infiltrating leucocytes and the resident skin, via a number of inflammatory cytokines, chemokines, and mediators produced in the skin under regulation of cellular immune systems. By contrast, the pathogenesis of PPP has been poorly investigated