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See Latest ArticlesThe inhibitory fciib receptor dampens tlr4-mediated immune responses and is selectively up-regulated on dendritic cells from rheumatoid arthritis patients with quiescent disease
Journal of Immunology, 09/28/09
Wenink MH et al. – Blocking FcgammaRIIb with specific Abs fully abrogated these effects demonstrating the full dependence on the inhibitory FcgammaRIIb in the induction of these phenomena. This TLR4–FcgammaRIIb interaction was shown to dependent on the PI3K and Akt pathway.
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Today in Rheumatology...keeping you current
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