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See Latest ArticlesA Systematic Review and Meta-analysis of the Efficacy and Safety of Etanercept for Treating Rheumatoid Arthritis
Scandinavian Journal of Immunology, 09/14/09
Wiens A et al. – In the efficacy meta–analysis, a greater number of ETA–treated patients achieved the efficacy criteria within 6 months of treatment, where the relative risk (RR) was 2.94 for achieving ACR20, 5.28 for ACR50 and 4.83 for ACR70. After 1 year, the RR for achieving ACR20, ACR50 and ACR70 were 1.14, 1.36 and 1.56, respectively. This response rates were higher for ETA–treated patients in comparison with control group patients. For safety, there were no statistically significant differences between treated patients and controls. This was also confirmed by withdrawals as a result of adverse events, which were not statistically different between the two groups. However, more patients withdrew from control groups because of a lack of efficacy asEtanercept compared with ETA groups
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