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Oxnard GR et al. – The authors present Tools of Human Investigation (THI), a two–week rotation offered during the second year of residency. The goals of THI are to provide seminar–based exposure to research methodologies, to impart the tools required to critically appraise the scientific literature, and to provide a small–group forum for career discussions. These three goals are achieved by drawing on a group of research faculty to lead sessions that combine didactics with career development guidance. A course like THI is one innovative way to stimulate interest in human research during residency that could help bridge the discontinuity between the research explorations promoted during medical school and the rigorous expectations of fellowship.

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