Med Student Medical News about hypertension; first-line drugs; low-dose thiazides

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First-line drugs for hypertension
Cochrane Reviews, 07/14/09

Wright JM et al. - In this review health outcomes resulting from 4 drug classes are summarized. Most of the evidence demonstrated that first-line low-dose thiazides reduce mortality and morbidity (stroke, heart attack and heart failure). No other drug class improved health outcomes better than low-dose thiazides, and beta-blockers and high-dose thiazides were inferior. Low-dose thiazides should be the first choice drug in most patients with elevated blood pressure. Fortunately, thiazides are also very inexpensive.