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Chattopadhyay A et al. - Prevalence/incidence of Helicobater pylori (Hp) is reduced in HIV/AIDS. HIV-infection may alter the prevalence/incidence or pathology of Helicobacter pylori (Hp) infection. Secretory leukocyte protease inhibitor (SLPI) is an important broad spectrum innate immunity component that has anti-bacterial and HIV-1 inhibitory activity in different mucosal secretions and possibly in the local mucosal tissue milieu.

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