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See Latest ArticlesDexamethasone and hypoxia upregulate CXCR4 expression in myeloma cells
Leukemia and Lymphoma, 07/02/09
Kim SW et al. - Incubation of cells under hypoxic conditions (1% O2) also induced upregulation of CXCR4 in the cytoplasm and on the cell surface and enhanced chemotaxis in response to stromal cell-derived factor-1 (SDF-1). Cell surface CXCR4 expression was more prominent in annexin V-positive apoptotic cells. Given the roles of the SDF-1/CXCR4 axis in the development and progression of myeloma, CXCR4-downregulating agents may enhance the antitumor effects of dexamethasone.
Today in Dermatology...keeping you current
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Novel Therapies for Pemphigus Vulgaris: An Overview
Drugs & Aging, 09/21/09
Erysipeloid: a review
Clinical and Experimental Dermatology, 09/18/09
Skin fusion on the fingers and toes of an adolescent girl
The Clinical Advisor, 09/09/09
Today in Hematology/Oncology...keeping you current
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Risk of dying from prostate cancer in men randomized to screening
Cancer, 10/13/09
Local excision alone without irradiation for ductal carcinoma in situ of the breast: A trial of the Eastern Cooperative Oncology Group
Journal of Clinical Oncology, 10/19/09
Nonsteroidal anti-inflammatory drugs
Cancer, 10/16/09
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