Methodological considerations for observational studies of acute kidney injury using existing data sources
James M et al. - Acute kidney injury (AKI), as defined by small, often reversible changes in kidney function, has recently been recognized as an important complication in hospitalized patients, and has been consistently associated with prolonged hospital length of stay, increased associated costs and short-term mortality. This review explores several methodological issues relevant to the design and conduct of observational studies that employ preexisting laboratory, administrative or research databases and that examine AKI as an outcome or an exposure. [more...]
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