Medication compliance in ischaemic stroke patients Internal Medicine Journal, 04/18/2012

Johnson C et al. – Adherence to secondary stroke prevention medication was between 87% and 100% at 6 weeks with similar findings at 6 months after discharge. The authors speculate that these high compliance rates may be due to one–on–one stroke nurse counselling and the use of stroke information packs, which include information about the importance of adherence to secondary prevention medication.

• The Auckland City Hospital Stroke database was used to identify consecutive patients with ischaemic stroke over a three–month period.
• Participants were contacted and invited to participate in a telephone questionnaire that asked about current medications.
• GPs were also asked to list the medications their patients were taking.

• Fifty–one patients were approached to participate of whom 48 consented to be interviewed at 6 weeks and 47 at 6 months.
• At 6 weeks, 36 of 38 (95%) were compliant with aspirin, 12 of 13 (92%) dipyridamole, 8 of 9 (88%) warfarin, 36 of 41 (88%) statins, 33 of 38 (87%) antihypertensive medications, and 7 of 7 (100%) diabetes medications.
• At 6 months, 97% were compliant with aspirin, 100% dipyridamole, 100% warfarin, 94% statins, 91% antihypertensive medications, and 100% diabetes medications.
• Natural or herbal remedy use was reported by 10 of 48 (21%) at 6 weeks and 11 of 47 (23%) at 6 months.
• Blister packs were used by 8 of 48 (17%) at 6 weeks and 5 of 47 (11%) at 6 months.