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Cytoprotective effect of hyaluronic acid and hydroxypropyl methylcellulose against DNA damage induced by thimerosal in Chang conjunctival cells
Graefe's Archive for Clinical and Experimental Ophthalmology, 07/16/2012
Ye J et al. – Thimerosal (Thi) can induce DNA damage in human conjunctival epithelial cells, probably due to oxidative stress. hyaluronic Acid (HA) and hydroxypropyl methylcellulose (HPMC) are protective agents that have antioxidant properties and can decrease DNA damage induced by Thi. Pretreatment of 0.3 % HA may be more protective of the ocular surface than 0.3 % HPMC.
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