Arterial stiffness is associated with increased monocyte expression of adiponectin receptor mrna and protein in patients with coronary artery disease
American Journal of Hypertension, 07/06/2012
Ikonomidis I et al. – Increased mRNA and protein expression of adiponectin receptors is related with increased aortic stiffness, coronary and peripheral atherosclerosis in patients with coronary artery disease (CAD). The interrelation of AdipoR2 with inflammatory markers, PWV and intima–media thickness (IMT) suggests a compensatory increase of these receptors to counteract the excess inflammatory and atherogenic process in CAD. Thus, adiponectin receptors may provide a potential therapeutic target of agents activating their beneficial action.