Spartalis ED et al. – The authors report a case of an 83–year–old female patient who was admitted to the department with a giant mediastinal mass that had caused progressive spinal distortion and weight loss. The clinical and laboratory investigations that followed revealed one of the largest thymomas ever reported in the medical literature, presenting as a mass lesion placed at the left hemithorax. The patient underwent complete surgical excision of the tumor via a median sternotomy. Two years after the operation, the patient showed significant improvement in her posture, no pulmonary discomfort, and a gain of 20 kg; she remains disease free based on radiographic investigations.
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