Hyperemesis gravidarum and risks of placental dysfunction disorders: a population-based cohort study
BJOG: An International Journal of Obstetrics and Gynaecology,  Clinical Article

Bolin M. et al. – To study whether pregnancies complicated by hyperemesis gravidarum in the first (<12 weeks) or second (12–21 weeks) trimester are associated with placental dysfunction disorders.It was seen that there is an association between hyperemesis gravidarum and placental dysfunction disorders, which is especially strong for women with hyperemesis gravidarum in the second trimester.

Methods

  • It is a Swedish Population–based cohort study.
  • Study population included all pregnancies in the Swedish Medical Birth Register estimated to have started on 1 January 1997 or later and ended in a single birth on 31 December 2009 or earlier (n = 1 156 050).
  • Odds ratios with 95% confidence intervals were estimated for placental dysfunction disorders in women with an inpatient diagnosis of hyperemesis gravidarum, using women without inpatient diagnosis of hyperemesis gravidarum as reference.
  • Risks were adjusted for maternal age, parity, body mass index, height, smoking, cohabitation with the infant's father, infant's sex, mother's country of birth, education, presence of hyperthyreosis, pregestational diabetes mellitus, chronic hypertension and year of infant birth.
  • Main outcome measures were Placental dysfunction disorders, i.e. pre–eclampsia, placental abruption, stillbirth and small for gestational age (SGA).

Results

  • Women with hyperemesis gravidarum in the first trimester had only a slightly increased risk of pre–eclampsia.
  • Women with hyperemesis gravidarum with first admission in the second trimester had a more than doubled risk of preterm (<37 weeks) pre–eclampsia, a threefold increased risk of placental abruption and a 39% increased risk of an SGA birth (adjusted odds ratios [95% confidence intervals] were: 2.09 [1.38–3.16], 3.07 [1.88–5.00] and 1.39 [1.06–1.83], respectively).

Please login or register to follow this author.
Are you sure you want to Unfollow this Author?
► Click here to access PubMed, Publisher and related articles...
<< Previous Article | Next Article >>

Your Unread Messages in Medical Student

See All >> Messages include industry-sponsored communications and special communications from MDLinx

Most Popular Medical Student Articles

1 Possible association between vitamin D deficiency and restless legs syndrome Full Text Neuropsychiatric Disease and Treatment, June 6, 2014    Free full text    Clinical Article

2 Chronic idiopathic axonal polyneuropathy and vitamin B6: a controlled population-based study Journal of the Peripheral Nervous System, June 6, 2014    Clinical Article

3 Pathology residency training: time for a new paradigm Human Pathology, March 25, 2014    Clinical Article

4 Systemic sclerosis: Comparison of efficacy of oral cyclophosphamide and azathioprine on skin score and pulmonary involvement--a retrospective study Rheumatology International, May 8, 2014    Clinical Article

5 Slowing of neurodegeneration in Parkinson's disease and Huntington's disease: future therapeutic perspectives The Lancet, June 20, 2014    Review Article    Clinical Article

6 Nuts in the prevention and treatment of metabolic syndrome American Journal of Clinical Nutrition, June 5, 2014    Review Article

7 Nut consumption and risk of type 2 diabetes, cardiovascular disease, and all-cause mortality: a systematic review and meta-analysis American Journal of Clinical Nutrition, June 4, 2014    Evidence Based Medicine    Review Article

8 Foreign-trained physicians frustrated at lack of residency positions, “brain waste,” when they move to higher-income countries, new study finds St. Michael's Hospital, June 27, 2014

9 Psychiatric disorders from childhood to adulthood in 22q11.2 deletion syndrome: Results from the International Consortium on Brain and Behavior in 22q11.2 Deletion Syndrome American Journal of Psychiatry, June 18, 2014    Clinical Article

10 Low vitamin D as a risk factor for the development of myalgia in patients taking high-dose simvastatin: A retrospective review Clinical Therapeutics, April 17, 2014    Review Article

11 Vitamin D status and Parkinson's disease: A systematic review and meta-analysis Neurological Sciences, June 5, 2014    Review Article

12 Consumption of nuts and legumes and risk of incident ischemic heart disease, stroke, and diabetes: a systematic review and meta-analysis American Journal of Clinical Nutrition, June 19, 2014    Evidence Based Medicine    Review Article

13 Sugar sweetened beverages consumption and risk of coronary heart disease: A meta-analysis of prospective studies Atherosclerosis, April 11, 2014    Evidence Based Medicine    Review Article

14 Calcium supplement intake and risk of cardiovascular disease in women Osteoporosis International, May 13, 2014    Clinical Article

15 Fish consumption, sleep, daily functioning, and heart rate variability Journal of Clinical Sleep Medicine, June 12, 2014    Clinical Article

16 Vitamin D supplementation and lipid profile: what does the best available evidence show Atherosclerosis, May 19, 2014    Evidence Based Medicine

17 Dance therapy in patients with chronic heart failure: A systematic review and a meta-analysis Clinical Rehabilitation, June 3, 2014    Evidence Based Medicine    Review Article

18 Fruits and vegetables consumption and risk of stroke Stroke, May 28, 2014    Evidence Based Medicine

19 Vitamin D supplements and cancer incidence and mortality: a meta-analysis British Journal of Cancer, June 12, 2014    Evidence Based Medicine

20 Effects of habitual coffee consumption on cardiometabolic disease, cardiovascular health, and all-cause mortality The Journal of Emergency Medicine, June 12, 2014    Clinical Article

Indexed Journals in Medical Student: Academic Medicine, BMC Medical Education, Medical Teachermore

Register now to view all the MDLinx contents (FREE)!

  • Stay current on the latest literature, research and clinical news
  • Get special communications and offers from MDLinx and our sponsors
  • Receive invitations to paid market research
View Samples and Register

Connect with us, stay current.

Receive the latest mecial news
updates for free via email

Sign up!

Subscribe to our free RSS feeds:

Get the latest news in your specialty automatically added to your newsreader or your personal My Yahoo!, Google, My MSN or My AOL page. Learn More

Close