Acral lesions of vitiligo: why are they resistant to photochemotherapy
Journal of the European Academy of Dermatology and Venereology, 08/16/2012
Esmat SM et al. – The surprisingly similar histochemical changes in response to PUVA in acral and non–acral lesions did not manifest with clinical repigmentation except in non–acral ones. Factors such as inherent lower melanocyte density, lower melanocyte stem cell reservoirs and/or lower baseline epidermal stem cell factor may be considered as possible play makers in this respect.