Is Polycystic Ovary Syndrome Another Risk Factor for Venous Thromboembolism? United States, 2003–2008
American Journal of Obstetrics and Gynecology, 08/16/2012
Okoroh EM et al. – Polycystic ovary syndrome (PCOS) might be a predisposing condition for venous thromboembolism (VTE), particularly among women aged 18–24. OC use might be protective.Methods
- Authors performed a cross–sectional analysis using Thomson Reuters MarketScan Commercial databases for the years 2003–2008.
- The association between VTE and PCOS among women aged 18–45 was assessed using age–stratified multivariable logistic regression models.
- Prevalence of VTE per 100,000 was 374.2 for PCOS women and 193.8 for women without PCOS.
- Compared with women without PCOS, those with PCOS were more likely to have VTE, (aOR 18–24 years, 3.26; 95% CI 2.61–4.08; aOR 25–34 years, 2.39; 95% CI 2.12–2.70; aOR 35–45 years, 2.05; 95% CI 1.84–2.38).
- A protective association (OR, 0.8; 95% CI 0.73–0.98) with OC use was noted for PCOS women.