Assessment of coronary artery disease by post-mortem cardiac MR
European Journal of Radiology, 08/17/2012
Ruder TD et al. – Chemical shift artifacts (CSA) is a marker of vessel patency. The presence of paired dark bands indicates stenosis. These criteria improve the ability of minimally invasive or virtual autopsy to detect coronary artery disease related deaths.
- The authors retrospectively compared autopsy and CT findings of 30 cases with significant (≥75%), insignificant (<75%), or absent coronary artery stenosis to post-mortem cardiac MR findings.
- The chi-square test was used to investigate if the occurrence of CSA depends on the presence or absence of stenosis.
- Sensitivity, specificity and predictive values were calculated for each finding.
- CSA indicates the absence of (significant) stenosis (p<0.001).
- The occurrence of paired dark bands in lieu of CSA on post-mortem cardiac MR suggests (significant) coronary arteries stenosis (p<0.001).
- Both findings have a high specificity but low sensitivity.