Inhibition of Apaf-1 as a potential therapeutic strategy to improve corneal quality
Acta Ophthalmologica, 08/17/2012
Herrero C et al. – The results hereby presented demonstrate a dual role of Apaf–1 inhibitors in preserving the cornea integrity by keeping TJ integrity and inhibiting apoptosis. The use of these inhibitors in the clinical setting could increase the availability and quality of tissue to be transplanted.