CYP450 phenotyping and accurate mass identification of metabolites of the 8-aminoquinoline, anti-malarial drug primaquine Full Text
Malaria Journal, 08/03/2012
Clinical Article
Pybus BS et al. – As a result of this work, CYP 2D6 and MAO–A have been implicated as the key enzymes associated with PQ metabolism, and metabolites previously identified as potentially playing a role in efficacy and haemolytic toxicity have been attributed to production via CYP 2D6 mediated pathways.



