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Timing and Efficacy of Alternative Methods of Sympathetic Blockade
Current Hypertension Reports, 08/17/2012
Briasoulis A et al. – Encouraging results from the recent Rheos Pivotal and Symplicity HTN–2 trials on the safety and efficacy of baroreflex activation therapy and renal denervation therapy, respectively, indicate that invasive approaches can safely reduce blood pressure in patients with resistant/refractory hypertension. These approaches, while still experimental in the US, are appropriate for those on more than three fully tolerated doses of antihypertensive medications whose blood pressure is not at goal, i.e. <140/90 mmHg.
