Recurrent hoarseness in a 12-year-old female patient with pachyonychia congenita type 1: case report and literature review
Advances in Dermatology and Allergology, 08/09/2012
Hogendorf A et al. – The authors report a phoniatric evaluation of a 12–year–old female with pachyonychia congenita type 1 and recurrent hoarseness. Pachyonychia congenita is an ultra rare genetic disorder of keratinisation that predominantly affects not only the nails, skin, hair, but also oral mucosae and larynx. Hoarseness is reported in 16% of patients with this disease and is attributed to laryngeal leukoplakia.