Sugar, Sex, and TGF-β in Diabetic Nephropathy
Seminars in Nephrology, 07/31/2012
Diamond–Stanic MK et al. – TGF–β is well known to play a critical role in diabetic kidney disease, and ongoing clinical studies are testing the potential therapeutic promise of inhibiting TGF–β production and action. An aspect of TGF–β action that has not received much attention is its potential role in explaining sex–related proclivity for kidney disease.