Long Term Clinical Consequences Of Urinary Tract Infections During Childhood
Acta Pediatrica, 07/16/2012
Toffolo A et al. – Renal function: there are no clear data to establish long–term consequences following UTIs during childhood. Most data seem to show that the outcome of renal function can already be delineated at first presentation or in the initial years of follow–up; only 0.4% of children with normal renal function at start presented a decrease during follow–up.
- Kidney scarring related to urinary tract infection in childhood has been considered the cause of serious long term clinical consequences.
- This assumption is now debated, as the advent of routine antenatal ultrasound in the 80s has shown that a consistent part of the changes previously attributed to post-infectious scarring is mainly due to congenital malformations.
- With the aim of determining what is presently known on the long term clinical consequences of UTIs in childhood, they performed a review of the literature on the relation between UTIs and blood pressure, renal function, growth and pregnancy-related complications.