Smartest Doc
Zinc Transporter 8 Autoantibodies and Their Association With SLC30A8 and HLA-DQ Genes Differ Between Immigrant and Swedish Patients With Newly Diagnosed Type 1 Diabetes in the Better Diabetes Diagnosis Study
Diabetes, 07/17/2012
Delli AJ et al. – Molecular simulation showed nonbinding of the relevant ZnT8–R peptide to DQ2, explaining in part a possible lack of tolerance to ZnT8–R. At diagnosis in non–Swedes, the presence of ZnT8–RA rather than ZnT8–WA was likely due to effects of HLA–DQ2 and the SLC30A8 CC(RR) genotypes.
