Safety and Immunogenicity of rSh28GST Antigen in Humans: Phase 1 Randomized Clinical Study of a Vaccine Candidate against Urinary Schistosomiasis Full Text
PLoS Neglected Tropical Diseases, 07/05/2012
Riveau G et al. – The rSh28GST in Alum did not induce any significant toxicity in healthy adults and generated a Th2–type immune response. Together with previous preclinical results, the data of safety, tolerability and quality of the specific immune response provide evidence that clinical trials with rSh28GST could be continued in humans as a potential vaccine candidate against urinary schistosomiasis.



